:root {
  --paper: #f8f7f3;
  --navy: #112b3a;
  --teal: #267d78;
  --teal-soft: #e4eeeb;
  --ink: #142e3e;
  --muted: #53636d;
  --rule: #bdc5c4;
  --serif: Georgia, "Times New Roman", serif;
  --sans: "Helvetica Neue", Arial, sans-serif;
}
* {
  box-sizing: border-box;
}
body {
  margin: 0;
  background: var(--paper);
  color: var(--ink);
  font-family: var(--sans);
  font-size: 16px;
  line-height: 1.6;
}
a {
  color: var(--teal);
  text-underline-offset: 4px;
}
a:hover {
  text-decoration: underline;
}
a:focus-visible,
button:focus-visible,
input:focus-visible,
select:focus-visible,
textarea:focus-visible {
  outline: 3px solid var(--teal);
  outline-offset: 5px;
}
.wrap {
  width: min(1320px, calc(100% - 88px));
  margin: auto;
}
.site-header {
  min-height: 108px;
  display: flex;
  align-items: center;
  justify-content: space-between;
  border-bottom: 1px solid #8c9b9e;
  gap: 30px;
}
.brand {
  text-decoration: none;
  color: var(--navy);
  white-space: nowrap;
}
.wordmark {
  font: 700 34px/1.1 var(--serif);
  letter-spacing: -1.8px;
}
.wordmark span {
  color: var(--teal);
}
nav {
  display: flex;
  gap: 30px;
  align-items: center;
}
nav a {
  color: var(--ink);
  text-decoration: none;
  font-size: 14px;
}
.rss-link {
  display: flex;
  gap: 7px;
}
.intro {
  padding: 48px 34px 34px;
}
.intro h1 {
  font: 500 clamp(56px, 6.4vw, 94px)/1.08 var(--serif);
  letter-spacing: -5px;
  margin: 0 0 17px;
}
.intro > p {
  font-size: 24px;
  margin: 0;
  color: #354b58;
}
.preview-notice {
  background: var(--teal-soft);
  padding: 13px 25px;
  display: flex;
  gap: 25px;
  align-items: center;
  font-size: 13px;
  margin: 0 0 27px;
  color: #4c626a;
}
.preview-notice strong {
  text-transform: uppercase;
  letter-spacing: 1.6px;
  font-size: 12px;
  color: #155e5b;
  border-right: 1px solid #a0b4b3;
  padding-right: 25px;
}
.feature {
  display: grid;
  grid-template-columns: 56% 44%;
  border-block: 1px solid #8c9b9e;
  min-height: 490px;
}
.feature-copy {
  padding: 45px 36px 46px;
}
.topic {
  font-size: 12px;
  text-transform: uppercase;
  letter-spacing: 1.7px;
  font-weight: 700;
  color: var(--teal);
}
.feature h2 {
  font: 500 clamp(35px, 4.3vw, 60px)/1.06 var(--serif);
  letter-spacing: -2.2px;
  margin: 24px 0;
}
.feature h2 a {
  color: var(--navy);
  text-decoration: none;
}
.feature p {
  font-size: 20px;
  line-height: 1.5;
  max-width: 590px;
  color: #435766;
  margin: 0 0 30px;
}
.button,
button {
  border: 1px solid var(--teal);
  padding: 15px 25px;
  color: var(--teal);
  background: transparent;
  font: 600 14px/1.3 var(--sans);
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 18px;
  text-decoration: none;
  cursor: pointer;
  min-height: 48px;
}
.button:hover,
button:hover {
  background: var(--teal-soft);
  text-decoration: none;
}
.editorial-art {
  background: #76a5a0;
  display: flex;
  flex-direction: column;
  justify-content: center;
  padding: 45px 55px;
  font: 500 clamp(35px, 4vw, 56px)/1.15 var(--serif);
  letter-spacing: -1.8px;
}
.editorial-art span:nth-child(2) {
  color: var(--paper);
}
.sponsor {
  text-align: center;
  padding: 24px 20px 28px;
  line-height: 1.5;
  min-height: 120px;
}
.micro {
  font-size: 10px;
  text-transform: uppercase;
  letter-spacing: 1.8px;
  color: var(--muted);
  display: block;
}
.sponsor p {
  margin: 12px 0 3px;
  font-size: 14px;
}
.sponsor > a {
  font-size: 12px;
}
.latest {
  border-top: 1px solid #8c9b9e;
  padding: 22px 0 20px;
}
.section-heading {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 20px;
}
.section-heading h2 {
  font: 500 43px/1.2 var(--serif);
  letter-spacing: -1.5px;
  margin: 0 0 22px;
}
.section-heading > a {
  font-size: 14px;
  text-decoration: none;
  white-space: nowrap;
}
.review-row {
  display: grid;
  grid-template-columns: 18% 30% 36% 16%;
  gap: 0;
  padding: 26px 22px;
  border-bottom: 1px solid var(--rule);
  align-items: center;
}
.review-row:last-child {
  border: 0;
}
.review-row > .topic {
  padding-right: 24px;
  line-height: 1.7;
}
.review-row h3 {
  border-left: 1px solid var(--rule);
  padding: 0 30px;
  margin: 0;
  font: 500 25px/1.23 var(--serif);
  letter-spacing: -0.5px;
}
.review-row h3 a {
  color: var(--ink);
  text-decoration: none;
}
.review-row p {
  font-size: 14px;
  line-height: 1.5;
  color: var(--muted);
  margin: 0;
  padding: 0 20px;
}
.text-link {
  font-size: 13px;
  white-space: nowrap;
  text-decoration: none;
  text-align: right;
}
.rss-band {
  background: var(--navy);
  color: var(--paper);
  padding: 40px 0;
}
.rss-band > .wrap {
  display: flex;
  justify-content: space-between;
  align-items: center;
  gap: 35px;
  padding: 0 22px;
}
.rss-band h2 {
  font: 500 42px/1.15 var(--serif);
  letter-spacing: -1.5px;
  margin: 0 0 9px;
}
.rss-band p {
  color: #d0dce0;
  margin: 0;
  font-size: 16px;
}
.light {
  border-color: #d4e4e4;
  color: var(--paper);
  white-space: nowrap;
}
.light:hover {
  color: var(--navy);
}
.site-footer {
  border-top: 1px solid #8c9b9e;
  margin-top: 27px;
  padding: 24px 12px;
  display: grid;
  grid-template-columns: 1fr 1fr;
  align-items: center;
  gap: 17px;
}
.site-footer .wordmark {
  font-size: 26px;
  letter-spacing: -1.2px;
}
.site-footer nav {
  justify-content: flex-end;
  gap: 24px;
}
.site-footer nav a {
  font-size: 12px;
  color: #47636c;
}
.site-footer p {
  font-size: 12px;
  color: #63737d;
  margin: 0;
}
.site-footer p:last-child {
  text-align: right;
}
.page {
  padding: 48px 24px 70px;
  min-height: 65vh;
}
h1 {
  font: 500 clamp(42px, 5vw, 66px)/1.1 var(--serif);
  letter-spacing: -2px;
  margin: 0 0 22px;
}
.lede {
  font-size: 23px;
  line-height: 1.5;
  color: #4e6470;
  margin-top: 0;
}
.back-link {
  display: inline-block;
  font-size: 14px;
  text-decoration: none;
  margin-bottom: 32px;
}
.article-header {
  max-width: 950px;
  margin: 0 auto 45px;
  padding-top: 10px;
}
.article-header h1 {
  margin-top: 20px;
}
.byline {
  font-size: 13px;
  color: var(--muted);
  border-block: 1px solid var(--rule);
  padding: 15px 0;
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  gap: 12px;
}
.article-grid {
  display: grid;
  grid-template-columns: minmax(0, 760px) 260px;
  justify-content: center;
  gap: 80px;
}
.prose {
  font: 400 20px/1.8 var(--serif);
  overflow-wrap: anywhere;
}
.prose h2 {
  font: 500 31px/1.2 var(--serif);
  letter-spacing: -0.5px;
  margin: 40px 0 16px;
}
.prose h3 {
  font-size: 24px;
}
.prose p {
  margin: 0 0 23px;
}
.standalone {
  max-width: 760px;
  margin: 0 auto;
}
.callout {
  background: var(--teal-soft);
  border-left: 3px solid var(--teal);
  padding: 22px 26px;
  margin: 0 0 28px;
  font: 400 15px/1.6 var(--sans);
}
.callout p {
  margin: 8px 0;
}
.callout strong {
  font-weight: 600;
}
.source-box {
  border-top: 1px solid var(--rule);
  margin-top: 40px;
  font: 400 15px/1.7 var(--sans);
}
.article-aside {
  padding-top: 15px;
  font-size: 14px;
  color: var(--muted);
}
.article-aside > a {
  display: block;
  margin: 15px 0;
}
.article-aside hr {
  border: 0;
  border-top: 1px solid var(--rule);
  margin: 30px 0;
}
.article-aside .sponsor {
  border-top: 1px solid var(--rule);
  margin-top: 35px;
  padding: 20px 0;
}
.filters {
  display: flex;
  align-items: end;
  gap: 20px;
  padding: 25px 0;
  border-bottom: 1px solid var(--rule);
  margin-bottom: 10px;
}
.filters label:first-child {
  flex: 1;
}
.filters a {
  font-size: 13px;
  padding-bottom: 12px;
}
label {
  display: flex;
  flex-direction: column;
  gap: 8px;
  font-size: 13px;
  font-weight: 600;
  color: #3c5663;
}
input,
select,
textarea {
  font: 400 16px/1.5 var(--sans);
  padding: 12px 14px;
  border: 1px solid #9bafaf;
  border-radius: 0;
  background: #fffefa;
  color: var(--ink);
  width: 100%;
}
textarea {
  resize: vertical;
}
.filters select {
  min-width: 210px;
}
.empty {
  padding: 60px 20px;
}
.empty h2 {
  font: 400 40px var(--serif);
}
.login-box {
  max-width: 660px;
  margin: 25px auto;
}
.login-box h1 {
  margin: 20px 0;
}
.login-box form {
  display: grid;
  gap: 25px;
  margin-top: 30px;
}
.error {
  color: #9b342d;
}
.desk-actions {
  display: flex;
  gap: 35px;
  align-items: center;
  margin: 30px 0;
}
.editor-list {
  border-top: 1px solid var(--rule);
  margin: 25px 0;
}
.editor-item {
  display: flex;
  justify-content: space-between;
  align-items: center;
  border-bottom: 1px solid var(--rule);
  padding: 23px 0;
  gap: 25px;
  text-decoration: none;
  color: var(--navy);
}
.editor-item strong {
  font: 500 25px var(--serif);
}
.editor-item small {
  display: block;
  font-size: 12px;
  color: var(--muted);
  margin-top: 8px;
}
.status {
  text-transform: uppercase;
  font-size: 11px;
  letter-spacing: 1px;
  color: var(--teal);
}
.muted {
  font-size: 13px;
  color: var(--muted);
}
.editor-form {
  max-width: 1040px;
  display: grid;
  gap: 25px;
  margin: 35px 0;
}
.form-grid {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 22px;
}
.editor-form button {
  justify-self: start;
  background: var(--navy);
  color: white;
  border-color: var(--navy);
}
.editor-form button:hover {
  background: var(--teal);
}
.body-editor {
  font-family: ui-monospace, monospace;
  font-size: 14px;
}
.workflow {
  border-top: 1px solid var(--rule);
  margin-top: 45px;
  padding-top: 20px;
}
.workflow h2 {
  font: 400 32px var(--serif);
}
.workflow-buttons {
  display: flex;
  gap: 15px;
  flex-wrap: wrap;
}
.secondary {
  border-color: var(--rule);
  color: var(--muted);
}
.private-banner {
  padding: 20px 24px;
  background: var(--teal-soft);
  display: flex;
  justify-content: space-between;
  gap: 15px;
}
.feed-copy {
  padding: 20px;
  background: var(--teal-soft);
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 15px;
  font-size: 14px;
}
.feed-copy code {
  overflow-wrap: anywhere;
}
.check {
  display: flex;
  flex-direction: row;
  align-items: center;
}
.check input {
  width: auto;
}
.skip {
  position: absolute;
  top: -100px;
  left: 15px;
  background: var(--paper);
  z-index: 10;
  padding: 12px;
}
.skip:focus {
  top: 5px;
}
@media (min-width: 1500px) {
  .intro h1 {
    font-size: 96px;
  }
}
@media (max-width: 1000px) {
  .wrap {
    width: calc(100% - 48px);
  }
  .site-header {
    gap: 15px;
    flex-wrap: wrap;
    padding: 20px 0;
  }
  .wordmark {
    font-size: 30px;
  }
  nav {
    gap: 20px;
  }
  .intro {
    padding: 35px 12px;
  }
  .intro h1 {
    letter-spacing: -3px;
  }
  .intro > p {
    font-size: 20px;
  }
  .feature-copy {
    padding: 32px 25px;
  }
  .feature h2 {
    font-size: 43px;
  }
  .feature p {
    font-size: 17px;
  }
  .editorial-art {
    padding: 30px;
    font-size: 43px;
  }
  .review-row {
    grid-template-columns: 20% 38% 42%;
    padding: 23px 10px;
  }
  .review-row p {
    padding-right: 0;
  }
  .review-row .text-link {
    grid-column: 2/4;
    text-align: left;
    padding: 15px 30px 0;
  }
  .rss-band h2 {
    font-size: 34px;
  }
  .site-footer {
    grid-template-columns: 1fr;
  }
  .site-footer nav {
    justify-content: flex-start;
  }
  .site-footer p:last-child {
    text-align: left;
  }
  .article-grid {
    grid-template-columns: minmax(0, 700px);
    gap: 20px;
  }
  .article-aside {
    border-top: 1px solid var(--rule);
    margin-top: 35px;
  }
  .article-aside .sponsor {
    margin-top: 20px;
  }
  .section-heading {
    align-items: flex-start;
  }
  .page {
    padding-inline: 10px;
  }
}
@media (max-width: 640px) {
  .wrap {
    width: calc(100% - 36px);
  }
  .site-header {
    min-height: 116px;
    gap: 20px;
  }
  .wordmark {
    font-size: 29px;
  }
  .site-header nav {
    width: 100%;
    justify-content: space-between;
    gap: 9px;
  }
  .site-header nav a {
    font-size: 11px;
  }
  .intro {
    padding: 34px 0 26px;
  }
  .intro h1 {
    font-size: 54px;
    letter-spacing: -2.7px;
    line-height: 1.02;
  }
  .intro > p {
    font-size: 18px;
    line-height: 1.5;
  }
  .preview-notice {
    display: block;
    padding: 14px 16px;
    font-size: 12px;
    margin-bottom: 22px;
  }
  .preview-notice strong {
    border: 0;
    display: block;
    margin-bottom: 6px;
  }
  .feature {
    grid-template-columns: 1fr;
  }
  .feature-copy {
    padding: 27px 12px 34px;
  }
  .feature h2 {
    font-size: 43px;
    letter-spacing: -1.7px;
  }
  .feature p {
    font-size: 17px;
  }
  .editorial-art {
    min-height: 280px;
    padding: 30px 35px;
    font-size: 45px;
  }
  .editorial-art br {
    display: none;
  }
  .sponsor {
    padding: 22px 10px;
  }
  .section-heading h2 {
    font-size: 34px;
    letter-spacing: -1px;
  }
  .section-heading > a {
    font-size: 12px;
    margin-top: 8px;
  }
  .review-row {
    grid-template-columns: 1fr;
    padding: 24px 5px;
  }
  .review-row h3 {
    border: 0;
    padding: 12px 0;
    font-size: 28px;
  }
  .review-row p {
    padding: 0;
    font-size: 14px;
  }
  .review-row .text-link {
    grid-column: auto;
    padding: 16px 0 0;
  }
  .rss-band {
    padding: 30px 0;
  }
  .rss-band > .wrap {
    display: block;
    padding: 0 5px;
  }
  .rss-band h2 {
    font-size: 35px;
    line-height: 1.1;
  }
  .rss-band p {
    font-size: 15px;
  }
  .rss-band .button {
    margin-top: 25px;
  }
  .site-footer {
    padding: 23px 2px;
    gap: 18px;
  }
  .site-footer nav {
    gap: 14px;
    flex-wrap: wrap;
  }
  .site-footer nav a {
    font-size: 11px;
  }
  .page {
    padding: 30px 0 50px;
  }
  h1 {
    font-size: 44px;
    letter-spacing: -1.5px;
  }
  .lede {
    font-size: 19px;
  }
  .article-header {
    margin-bottom: 30px;
  }
  .prose {
    font-size: 19px;
    line-height: 1.75;
  }
  .prose h2 {
    font-size: 29px;
  }
  .filters {
    display: grid;
    grid-template-columns: 1fr;
    gap: 15px;
  }
  .filters select {
    min-width: 0;
  }
  .filters a {
    padding: 0;
  }
  .form-grid {
    grid-template-columns: 1fr;
  }
  .section-heading {
    flex-direction: column;
  }
  .editor-item {
    gap: 12px;
    flex-wrap: wrap;
  }
  .editor-item strong {
    font-size: 23px;
  }
  .private-banner {
    flex-direction: column;
  }
  .feed-copy {
    padding: 15px;
  }
  .login-box {
    margin: 10px auto;
  }
  .login-box h1 {
    font-size: 44px;
  }
}

/* Evergreen research reference */
.site-header nav {
  flex-wrap: wrap;
}
.guide-layout {
  display: grid;
  grid-template-columns: 240px minmax(0, 760px);
  gap: 52px;
  align-items: start;
  justify-content: center;
}
.guide-toc {
  position: sticky;
  top: 24px;
  display: flex;
  flex-direction: column;
  align-items: stretch;
  gap: 12px;
  padding: 22px;
  border: 1px solid var(--rule);
  border-radius: 4px;
  max-height: calc(100vh - 48px);
  overflow: auto;
}
.guide-toc strong {
  font-size: 12px;
  letter-spacing: 1px;
  text-transform: uppercase;
}
.guide-toc a {
  font-size: 14px;
  line-height: 1.5;
  text-decoration: underline;
  text-underline-offset: 3px;
}
.guide-body {
  min-width: 0;
}
.guide-body section {
  border-bottom: 1px solid var(--rule);
  padding-bottom: 28px;
  margin-bottom: 32px;
}
.guide-body h2,
.guide-sources li {
  scroll-margin-top: 28px;
}
.guide-body section:first-of-type h2 {
  margin-top: 0;
}
.guide-example {
  background: var(--teal-soft);
  padding: 24px;
  margin: 24px 0;
  border-left: 3px solid var(--teal);
}
.guide-example > strong {
  font: 600 15px/1.6 var(--sans);
}
.guide-example p:last-child {
  margin-bottom: 0;
}
.guide-definitions dt {
  font-weight: 600;
  margin-top: 22px;
}
.guide-definitions dd {
  margin: 6px 0 22px;
}
.guide-table-wrap {
  overflow-x: auto;
  margin: 24px 0;
}
.guide-body table {
  width: 100%;
  border-collapse: collapse;
  font: 400 16px/1.6 var(--sans);
}
.guide-body caption {
  text-align: left;
  font-size: 14px;
  color: var(--muted);
  margin-bottom: 12px;
}
.guide-body th,
.guide-body td {
  text-align: left;
  padding: 12px;
  border-bottom: 1px solid var(--rule);
}
.guide-body thead {
  background: var(--teal-soft);
}
.guide-risk-picture {
  padding: 24px;
  border: 1px solid var(--rule);
  margin: 24px 0;
}
.guide-risk-picture p {
  font: 400 15px/1.6 var(--sans);
  margin-bottom: 8px;
}
.guide-risk-track {
  height: 22px;
  background: #e2e8e7;
  margin-bottom: 20px;
  border-radius: 3px;
  overflow: hidden;
}
.guide-risk-track:last-child {
  margin-bottom: 0;
}
.guide-risk-track span {
  display: block;
  height: 100%;
  background: var(--teal);
}
.guide-risk-ten {
  width: 10%;
}
.guide-risk-five {
  width: 5%;
}
.guide-body .guide-citation,
.guide-back,
.guide-sources {
  font: 400 14px/1.7 var(--sans);
}
.guide-body .guide-citation {
  color: var(--muted);
}
.guide-back {
  text-underline-offset: 4px;
}
.guide-sources li {
  margin-bottom: 12px;
}
@media (max-width: 1000px) {
  .guide-layout {
    grid-template-columns: minmax(0, 760px);
    gap: 30px;
  }
  .guide-toc {
    position: static;
    max-height: none;
    display: grid;
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }
  .guide-toc strong {
    grid-column: 1 / -1;
  }
}
@media (max-width: 640px) {
  .guide-toc {
    grid-template-columns: minmax(0, 1fr);
    padding: 20px;
  }
  .guide-example,
  .guide-risk-picture {
    padding: 20px;
  }
  .guide-body th,
  .guide-body td {
    padding: 8px;
  }
}

.prose > table {
  display: block;
  max-width: 100%;
  overflow-x: auto;
  border-collapse: collapse;
  font: 400 15px/1.6 var(--sans);
  margin: 24px 0;
}
.prose > table th,
.prose > table td {
  padding: 12px;
  border-bottom: 1px solid var(--rule);
  text-align: left;
  vertical-align: top;
}
.prose > table thead {
  background: var(--teal-soft);
}

/* Clinical tools: readable forms paired with definitions and explicit branches. */
.tools-page { padding-bottom: 80px; }
.tools-jump { display:flex; flex-wrap:wrap; gap:12px 28px; padding:24px 0; border-bottom:1px solid var(--rule); }
.tool-panel { display:grid; grid-template-columns:minmax(0,1fr) minmax(0,1fr); gap:64px; padding:56px 0; border-bottom:1px solid var(--rule); scroll-margin-top:24px; }
.tools-page h2 { font:400 clamp(30px,4vw,46px)/1.15 var(--serif); margin:12px 0 24px; }
.tool-form { background:white; padding:28px; border:1px solid var(--rule); align-self:start; min-width:0; }
.tool-form label { display:block; margin-bottom:20px; }
.tool-form input,.tool-form select { width:100%; min-height:46px; margin-top:8px; }
.tool-form fieldset { padding:0; border:0; min-width:0; }
.tool-form legend { font-weight:600; margin-bottom:22px; }
.tool-question span { display:block; font-weight:600; }
.tool-question small,.tool-note { display:block; color:var(--muted); font-size:14px; line-height:1.6; }
.tool-input-pair { display:grid; grid-template-columns:1fr 1fr; gap:18px; }
.tool-actions { display:flex; flex-wrap:wrap; gap:12px; }
.tool-result { margin-top:24px; padding:20px; background:var(--teal-soft); border-left:3px solid var(--teal); overflow-wrap:anywhere; }
.pathway-section { padding-top:56px; scroll-margin-top:24px; }
.pathway-grid { display:grid; grid-template-columns:minmax(0,1.2fr) minmax(0,1fr); gap:48px; margin-top:32px; }
.pathway-node { padding:24px; border:1px solid var(--rule); background:white; margin-bottom:12px; }
.pathway-node p { margin:10px 0 0; }
.pathway-node.is-active { border:3px solid var(--teal); background:var(--teal-soft); }
.pathway-node.is-active::before { content:'Selected discussion branch'; display:block; font-weight:600; margin-bottom:12px; }
.pathway-arrow { text-align:center; color:var(--muted); margin:10px; }
.tools-page details { font-size:14px; margin:24px 0; }
@media(max-width:900px) { .tool-panel,.pathway-grid { grid-template-columns:minmax(0,1fr); gap:28px; } }
@media(max-width:480px) { .tool-form { padding:20px; } .tool-input-pair { grid-template-columns:minmax(0,1fr); gap:0; } }